The Autoantibody Profile 2 Blood Test is a panel used to detect a wide range of autoantibodies. This test is typically ordered when there is a high suspicion of autoimmune disease or when initial testing has provided inconclusive results. It helps in diagnosing more specific or rare autoimmune conditions and in assessing disease progression or complications.

Autoantibodies Tested in Autoantibody Profile 2:

  • Thyroid Abs (Thyroglobulin + Thyroid Peroxidase Abs)
  • Islet Cell Antibodies
  • Adrenal Antibodies
  • Gastric Parietal Autoantibodies
  • Gonadal (Ovarian) Abs

When Is the Autoantibody Profile 2 Test Ordered?

This profile is typically ordered when a patient presents with symptoms suggesting an autoimmune disease, particularly when:

  • Initial autoantibody testing was inconclusive.
  • There is a suspicion of more specific or rare autoimmune disorders.
  • The patient has unexplained inflammation, multisystem involvement, or vascular symptoms.

Conditions Often Diagnosed with Autoantibody Profile 2:

  • Primary Biliary Cirrhosis (PBC)
  • Autoimmune Hepatitis
  • Antiphospholipid Syndrome (APS)
  • Wegener’s Granulomatosis (Granulomatosis with Polyangiitis)
  • Microscopic Polyangiitis
  • Polymyositis/Dermatomyositis
  • Mixed Connective Tissue Disease (MCTD)
  • Hashimoto’s Thyroiditis
  • Graves’ Disease
  • Drug-Induced Lupus
  • Vasculitis (various forms)

Conclusion:

The Autoantibody Profile 2 Blood Test is a more comprehensive and specific test panel designed to investigate complex autoimmune conditions. By detecting a broader range of autoantibodies, this profile aids in diagnosing rarer and more severe autoimmune diseases, often providing clarity when the results of basic tests like ANA are insufficient. It is an essential tool for diagnosing, monitoring, and managing autoimmune diseases with multi-organ involvement or atypical presentations.

Results – 2 days from Laboratory receiving sample

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