The Aspartate Transaminase (AST) Blood Test measures the level of AST, an enzyme found primarily in the liver and heart. This test helps diagnose liver damage and other conditions affecting the liver, heart, or muscles.

What Is AST?

AST, also known as SGOT (serum glutamic-oxaloacetic transaminase), is an enzyme that helps metabolize amino acids. While it is primarily concentrated in the liver and heart, AST is also found in smaller amounts in the muscles, kidneys, and brain. When these tissues are damaged, AST is released into the bloodstream, leading to elevated levels.

Why Is the AST Blood Test Performed?

This test is commonly ordered to:

  • Assess liver function and detect conditions like hepatitis, cirrhosis, or fatty liver disease.
  • Evaluate heart health in cases of suspected heart attack or other cardiac conditions.
  • Diagnose muscle disorders or injuries.
  • Monitor liver health during certain treatments or in individuals taking medications that affect the liver.

Symptoms That May Lead to an Aspartate Transaminase (AST) Blood Test

Your doctor may recommend an AST test if you experience:

  • Persistent fatigue or weakness
  • Abdominal pain or swelling
  • Jaundice (yellowing of the skin or eyes)
  • Dark urine or pale stool
  • Nausea or vomiting

How Is the Test Conducted?

  1. Sample Collection: A blood sample is taken from a vein in your arm.
  2. Lab Analysis: The sample is analyzed to determine AST levels.
  3. Results Interpretation:
    • Normal Range: Typically 10–40 units per liter (U/L), though this can vary by lab.
    • Elevated Levels: May indicate liver damage, heart issues, or muscle injury.

Common Conditions Linked to Elevated AST Levels

  • Liver Conditions: Hepatitis, cirrhosis, fatty liver disease, or liver tumors.
  • Heart Conditions: Myocardial infarction (heart attack) or heart failure.
  • Muscle Disorders: Rhabdomyolysis or muscle trauma.
  • Other Conditions: Acute pancreatitis or kidney disease.

Preparation and Risks

  • Preparation: No special preparation is usually required, but inform your doctor about any medications you are taking, as they may affect AST levels.
  • Risks: The test involves minimal risks, such as slight discomfort or bruising at the blood draw site.

To book please use the link below or call our friendly team on 01443 303003.

Back to Blood Tests