The Histamine Releasing Urticaria Blood Test is a specialised diagnostic tool used to identify chronic urticaria (hives) triggered by the release of histamine. This test is essential for understanding the underlying cause of persistent skin reactions and guiding effective treatment.

What Is Histamine Releasing Urticaria?

Histamine releasing urticaria refers to a condition where the body’s immune system causes histamine release, leading to hives or welts on the skin. This can occur due to autoimmune activity, allergies, or idiopathic (unknown) causes.

Why Is This Test Performed?

This blood test is recommended for individuals experiencing chronic hives or welts that are unexplained or persistent. Symptoms that may prompt this test include:

  • Recurrent red, itchy, or raised welts on the skin
  • Swelling of the skin (angioedema)
  • Flare-ups triggered by stress, pressure, heat, or certain foods
  • Hives lasting longer than six weeks

How Does the Test Work?

  1. Blood Sample Collection:
    • A small blood sample is taken from a vein, typically in your arm.
  2. Laboratory Analysis:
    • The sample is tested to measure histamine release and identify potential immune triggers.
  3. Results Interpretation:
    • Positive Test: Indicates histamine release as a cause of chronic urticaria, suggesting possible autoimmune or allergic triggers.
    • Negative Test: Suggests an alternative cause, requiring further investigation.

Understanding Test Results

  • Positive Results: May confirm histamine releasing urticaria, which could be linked to autoimmune processes or physical triggers.
  • Negative Results: Further diagnostic tests might be needed to explore other underlying causes, such as mast cell disorders or allergen sensitivity.

Preparation and Risks

  • Preparation: No special preparation is required, but inform your doctor about any medications, especially antihistamines, as they may interfere with the test.
  • Risks: Minimal risks, such as mild bruising or discomfort at the blood draw site.

Benefits of the Histamine Releasing Urticaria Test

  • Accurate Diagnosis: Pinpoints the role of histamine in chronic hives.
  • Personalised Care: Helps your healthcare provider create a targeted treatment plan.
  • Improved Quality of Life: Identifying and addressing the cause can reduce symptoms and improve daily life.

To book please use the link below or call our friendly team on 01443 303003.

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