A Vitamin B3 (niacin) blood test measures the level of niacin in the blood. Niacin is a water-soluble vitamin that plays essential roles in energy production, metabolism, and nervous system function. Here’s an overview of the Vitamin B3 blood test:

Purpose

  • Assess Nutritional Status: To evaluate niacin levels in individuals with symptoms of deficiency or those at risk.
  • Monitor Health Conditions: To monitor patients with conditions affecting niacin metabolism or absorption, such as certain gastrointestinal disorders.
  • Diagnose Deficiency: To confirm niacin deficiency in symptomatic individuals or those with specific health conditions.

Symptoms of Deficiency

  • Mild Deficiency: Fatigue, irritability, headaches, and digestive issues.
  • Severe Deficiency: Pellagra, characterised by dermatitis (skin inflammation and rash), diarrhoea, dementia, and potentially death if untreated.

Test Procedure

  1. Sample Collection: A blood sample is drawn from a vein, typically in the arm, using a needle.
  2. Preparation: Fasting for 4-6 hours before the test may be required. Inform the healthcare provider about any supplements or medications being taken.
  3. During the Test: The site is cleaned, a tourniquet is applied to make the veins more visible, and blood is collected into a vial.
  4. After the Test: A bandage is applied to the puncture site. The sample is sent to a laboratory for analysis.

Risks of the Test

  • Minor: Pain or discomfort at the needle site, bruising, or slight bleeding.
  • Rare: Infection at the puncture site or fainting.

Follow-Up

  • Deficiency: Increasing dietary intake of niacin through foods such as meat, poultry, fish, nuts, whole grains, and fortified cereals, or taking supplements as advised by a healthcare provider.
  • Monitoring: Regular monitoring for individuals at risk of niacin deficiency or those with conditions affecting niacin metabolism.

Special Considerations

  • Niacin Flush: High-dose niacin supplements can cause a temporary flushing reaction, characterised by reddening of the skin, itching, and warmth, which is generally harmless but can be uncomfortable.
  • Medication Interactions: Niacin supplements can interact with certain medications, such as cholesterol-lowering drugs (statins), so it’s important to discuss niacin supplementation with a healthcare provider.

Consulting with a healthcare professional is essential for interpreting test results and determining the appropriate course of action based on individual health needs and medical history.

Results – 5 days from Laboratory receiving sample